Chris Hemsworth has opened up about how learning of his heightened genetic risk for Alzheimer’s disease has reshaped the way he approaches health, work, and family.

The 41-year-old Thor actor first discovered the news while filming the Disney+ series Limitless, a documentary project focused on human longevity. Genetic testing revealed Hemsworth carries two copies of the APOE4 gene, one from each paren, placing him at an estimated eight to ten times higher risk of developing Alzheimer’s than someone without both copies.

It was a warning sign that became a big motivator to look after myself,” Hemsworth told the BBC. “It also felt like an opportunity to raise awareness for something so many people face.”

Alzheimer’s, according to the Cleveland Clinic, is the leading cause of dementia and progressively impacts memory, reasoning, and cognitive function.

The revelation sparked rumours that Hemsworth was retiring or already experiencing dementia, claims he strongly refutes. “It kind of p***ed me off,” he told Vanity Fair. “I’d been vulnerable and shared something personal, and suddenly the story became that I have dementia and I’m quitting acting.”

Instead, the actor says the diagnosis inspired him to make measured, lasting lifestyle changes. Gone is the “smash yourself every session” training mentality. “I used to think if I wasn’t crawling out of the gym, I hadn’t worked hard enough,” he told Body + Soul. “Now I’m more patient, I listen to my body, and I focus on the long game.”

Credit: Theo Wargo / Getty Images.
These days, Hemsworth’s routine includes mindfulness practices, solitude, and activities designed to support brain health alongside physical fitness. “Time without outside voices or stimulation is essential,” he said to Men’s Health.

He has also been exploring regenerative medicine, recently meeting Dr. Adeel Khan to learn about MUSE cells, specialised regenerative stem cells found in bone marrow and connective tissue. “The fact Dr. Khan works directly with the scientist who pioneered these cells gave me confidence,” Hemsworth wrote on Instagram.

One of the biggest shifts has been his work-life balance. Living in Byron Bay with wife Elsa Pataky and their three children, Hemsworth now weighs every project against the time it takes away from family. “Sometimes giving that extra 20 percent to work meant diminishing returns,” he reflected.

Though he’s skeptical of extreme biohacking trends, he believes in targeted, realistic health optimisation. “There’s no point in living longer if you’re isolated and unhappy,” he said. “I’m going to invest in my health, but I also want to enjoy life.”

Hemsworth sees mortality as something to face head-on. “Suffering comes from denying that death is inevitable,” he said. “We all have an expiration date.”

Longevity expert Dr. Peter Attia believes that with focused lifestyle changes, Hemsworth could bring his risk level back down to the population average, a prospect Hemsworth calls a “blessing” in disguise.

For now, the actor isn’t slowing down. He’s set to reprise his role in Avengers: Doomsday in 2026, and while he’s open to future solo Thor films, he’s choosing projects with greater purpose.

“It’s in the quieter moments that I make the best decisions,” he said, something his genetic discovery has made all the more important.