Cold sores, also known as fever blisters, are a common viral infection primarily caused by the herpes simplex virus type 1 (HSV-1). In some cases, herpes simplex virus type 2 (HSV-2)\u2014usually associated with genital herpes\u2014can also lead to cold sores, especially through oral-genital contact.<\/p>\n
What Causes Cold Sores?
\nCold sores are highly contagious and spread easily from person to person, most often through contact with infected saliva or skin. Common ways the virus is transmitted include:<\/p>\n
Direct contact: Kissing or sharing drinks, food, or utensils with an infected person.<\/p>\n
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\nIndirect contact: Using items contaminated with the virus, like towels, lip balm, or cutlery.<\/p>\n
Self-infection (Autoinoculation): Touching a cold sore and then touching other parts of the body, such as the eyes or genitals, can spread the virus.<\/p>\n
Recognizing the Symptoms
\nCold sores tend to follow a series of stages:<\/p>\n
Tingling or itching: A burning or itching sensation is often the first sign, occurring 1\u20132 days before the sore appears.
\nFormation of blisters: Small, fluid-filled blisters develop, usually near the lips but sometimes on the nose or gums.
\nBlister rupture: The blisters break open, forming painful, red sores. This is the most contagious stage.
\nScabbing: The sores dry out and develop a crust, which eventually falls off during healing.<\/p>\n
A typical outbreak lasts about 7 to 10 days. While the sores heal, the virus stays dormant in the body and can become active again during certain triggers.<\/p>\n
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\nWhat Triggers an Outbreak?
\nSeveral factors can reactivate the virus and cause new sores:<\/p>\n
Emotional or physical stress
\nExposure to sunlight or UV rays
\nHormonal shifts, such as those during menstruation or pregnancy
\nOther illnesses, including colds and fevers
\nWeakened immune system, due to medical treatments or health conditions
\nHow Are Cold Sores Treated?
\nThere\u2019s no permanent cure for cold sores, but treatments can help manage symptoms and speed up healing:<\/p>\n
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\n1. Antiviral pills: Medications like acyclovir, valacyclovir, or famciclovir can reduce the length and severity of an outbreak, especially if taken early.<\/p>\n
2. Topical antiviral creams: Help ease symptoms and may reduce viral spread.<\/p>\n
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\n3. Pain relievers: Over-the-counter medications like ibuprofen or acetaminophen, or numbing creams, can help relieve discomfort.<\/p>\n
4. Moisturizing balms or creams: Soothing lip products can reduce dryness and ease pain around the sores.<\/p>\n
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Tips for Prevention
\nTo avoid spreading cold sores or triggering outbreaks, try the following:<\/p>\n
Avoid kissing or close contact during an active outbreak<\/p>\n
Don\u2019t share personal items like lip balms, cutlery, or towels<\/p>\n
Use lip sunscreen if sun exposure is a known trigger<\/p>\n
Support your immune system through a balanced diet, regular exercise, and stress management<\/p>\n
When Should You See a Doctor?
\nIt\u2019s a good idea to consult a healthcare provider if:<\/p>\n
Outbreaks happen frequently or are unusually painful<\/p>\n
Over-the-counter remedies aren\u2019t helping<\/p>\n
The sores spread beyond the lips or grew significantly in size<\/p>\n
Pain interferes with eating, drinking, or speaking<\/p>\n
You have a weakened immune system, which can increase complications<\/p>\n
The cause of Alzheimer\u2019s may lie within your mouth<\/p>\n
Alzheimer\u2019s is the most popular reason of dementia in the UK, NHS notes. The exact cause of it is not fully understood such as increasing age, untreated depression, a family history of the condition, and lifestyle factors and conditions linked to cardiovascular diseases, among the rest.<\/p>\n
However, in recent years, an increasing number of scientific studies have found that Alzheimer\u2019s isn\u2019t just a disease, but an infection.
\nA 2019 study finds that Alzheimer\u2019s may be connected to gum disease.<\/p>\n
\u201cInfectious agents have been implied in the development and progression of Alzheimer\u2019s disease before, but the evidence of causation hasn\u2019t been convincing,\u201d Dr. Stephen Dominy, Cortexyme co-founder, explained.<\/p>\n
Looking at gingipains, the toxic enzymes of P. gingivalis, scientists explored that high gingipain levels were related to the presence of two other proteins already linked with the development of Alzheimer\u2019s: tau and ubiquitin.<\/p>\n
However, the team also found the presence of these toxic gingipains in the brains of deceased patients who were never diagnosed with Alzheimer\u2019s.<\/p>\n
The question is whether they would be diagnosed with the diseases had they been alive, or is it the Alzheimer\u2019s that cause poor oral care.<\/p>\n
\u201cOur identification of gingipain antigens in the brains of individuals with AD and also with AD pathology but no diagnosis of dementia argues that brain infection with P. gingivalis is not a result of poor dental care following the onset of dementia or a consequence of late-stage disease, but is an early event that can explain the pathology found in middle-aged individuals before cognitive decline,\u201d the authors explained in their paper.<\/p>\n
The mice experiment also revealed a decrease of amyloid-beta production and neuroinflammation because of a compound formulated by the company called COR388.<\/p>\n
\u201cDrugs targeting the bacteria\u2019s toxic proteins have so far only shown benefit in mice, yet with no new dementia treatments in over 15 years it\u2019s important that we test as many approaches as possible to tackle diseases like Alzheimer\u2019s,\u201d chief scientific officer David Reynolds from Alzheimer\u2019s Research said.<\/p>\n","protected":false},"excerpt":{"rendered":"
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